Bupivacaine Hydrochloride

Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.

General Details

Raw Steroid Powder Local Anesthetic USP Standard Bupivacaine Hydrochloride Bupivacaine HCL

 

Quick Detail:

 

English name: bupivacaine hydrochloride
English Synonyms: Bupivocoine HCl; Bupivacaine Hcl;Marcaina; BUPIVACAINE HYDROCHLORIDE ANHYDROUS
CAS: 14252-80-3
EINECS Number: 241-917-8
Formula: C18H31ClN2O2
MW: 342.9039
Molecular Structure:

 

Raw Steroid Powder Local Anesthetic USP Standard Bupivacaine Hydrochloride Bupivacaine HCL
Boiling point: 423.4 ° C at 760 mmHg
Flash Point: 209.9 ° C
Vapor Pressure: 2.24E-07mmHg at 25 ° C
Uses:After local anesthesia for surgery and postoperative analgesia

Assay:99%

Appearance:White crystalline powder

 

 

Description:

 

Anesthesia, local- Proparacaine and tetracaine are indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure, removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy.

 

Applications:

 

Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.

 

Bupivacaine Hydrochloride Usage:

 

Bupivacaine hydrochloride injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solution of Bupivacaine hydrochloride injection, USP may be autoclaved. Solution is clear and colorless.

 

Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue
of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine hydrochloride injection, USP – Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.
Bupivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.
Bupivacaine is used as a local (in only one area) anesthetic.
Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery,

or certain medical procedures.
Bupivacaine is also used as an anesthetic for dental procedures.
Bupivacaine may also be used for purposes not listed in this medication guide.

 

Related Products:

 

 

Local Anesthetic

 

Formestane

L-Thyroxine / Epinephrine Hydrochloride

Duagen / Dutasteride

Finasteride / Prostide

Procaine Hydrochloride

Lidocaine

Lidocaine Hydrochloride

Tetracaine

Tetracaine Hydrochloride

Prilocaine

Articaine Hydrochloride

Levobupivacaine Hydrochloride

Benzocaine / Ethyl 4-Aminobenzoate

Benzocaine Hydrochloride

Procaine

Procaine Hydrochloride

Propitocaine Hydrochloride

Pramoxine Hydrochloride

Proparacaine Hydrochloride

Dyclonine Hydrochloride

Dibucaine Hydrochloride

Bupivacaine Hydrochloride

Ropivacaine Mesylate

 

Bupivacaine Hydrochloride Specification:

 

TESTS SPECIFICATIONS
Description White crystalline powder.
Solubility Freely soluble in water and in alcohol; slightly soluble
in chloroform and in acetone.
IdentifIcation A: By IR, To match with working standard
B: By UV, To match with working standard
C: Chloride test, To Matching with the standard
PH 4.5 ~ 6.0
Water 4.0%~6.0%
Residue on ignition ≤ 0.1%
Heavy metals ≤ 0.001%
Limit of residual solvents Should be to match with the standard
Chromatographic purity Should be to match with the standard
Assay 98.5~101.5%
(on the anhydrous basis.)

 

 

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