Dyclonine Hydrochloride

Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt.

General Details

Dyclonine Local Anesthetic Agents 536-43-6 Dyclonine Hydrochloride Dyclonine HCL Powders For Topical Anesthesia

 

 

Basic View:

 
English name : dyclonine hydrochloride
English Name : Dyclonine, Hydrochloride; 4-butoxy-3-piperidinopropiophenone hydrochloride; Dyclonine HCL
CAS : 536-43-6
EINECS Number : 208-633-6
Formula : C18H28ClNO2
MW : 325.8734
Boiling point : 424.5 ° C at 760 mmHg
Flash Point : 210.5 ° C
Vapor Pressure: 2.06E-07mmHg at 25 ° C
Uses : For topical anesthesia
Assay : 99.72%
Appearance : White powder

 

COA:

 

Items Specifications Results
Appearance  A white or almost white crystalline A white powder
Identification A,B,C in Pass Complies
Melting Point 173 – 178 ℃ 174-177.5℃
Acidity(PH) 4.0 – 7.0 6.6
Loss on drying ≤ 1.0 % 0.33 %
Residue on ignition ≤ 0.2 % 0.034%
Assay 98 – 102 % 99.72%
CONCLUSION Pass USP 34

 

 

Description:

 

 

Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungicidal activity. Self-sterilizing action manifested by preparations containing the drug was considerably enhanced upon the addition of chlorobutanol. Results of in vitro tests employing microorganisms commonly involved in local infections indicated that the two agents in combination act synergistically
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Applications:

 

 

Has been used as a local anesthetic agent prior to laryngoscopy, bronchoscopy, esophagoscopy, or endotracheal intubation.

 

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Paracetamol

 

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