Sunifiram (DM-235)

Sunifiram (DM-235) is a piperazine derived ampakine-like drug which has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, including unifiram (DM-232).

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General Details

Sunifiram 314728-85-3 White Powder Pharmaceutical Raw Material Fitness Supplement

 

Description:

 

 

CAS: 314728-85-3

Molecular Formula:C14H18N2O2

Formula Weight:246.30492

Appearance: White or almost white crystalline power

Specification: 99.0%

 

Sunifiram (DM-235) is a piperazine derived ampakine-like drug which has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, including unifiram (DM-232).

 

Description:
Sunifiram is one of the latest additions to the racetam family and has been shown to be over 1000 times more potent than the original racetams. Although Sunifiram follows the same naming structure of the racetams it is technically not in this family as it differs by having a piperazine backbone instead of the usual pyrrolidine. With regards to the safety and action on the brain it is similar to the others, with strong ampakine modulation and mental stimulation. Sunifiram has a much sought after bonus of Long Term Potentiation or LTP which gives the user a boost in synaptic plasticity, giving and underlying benefit to learning and memory. Further enhancements to mental stimulation, and a boosted learning capability are substantial due to Sunifirams acetylcholine releasing actions.

 

 

How Does Sunifiram Work?  
The exact mechanism to explain how Sunifiram is able to have such a strong cognitive benefit is yet to be found, but scientist have identified some interesting models to show how some of these attributes may be better understood. One such mechanism is that of NMDA signaling which was confirmed after Sunifiram dosages were maintained for over 7 days. This can explain some of the NMDA-dependent Long Term Potentiation seen with Sunifiram use.Further studies have shown rodents with memory impairment (centered around the hippocampus) benefitted from Sunifiram administration, when their ability to complete training sessions was measured. Finally, Sunifiram injections were able to cause the release of acetylcholine, which was detected in the prefrontal cortex of laboratory mice.

 

Sunifiram  Benifits:

 

Sunifiram increases energy levels, allowing users to feel more motivated and eliminate
Sunifiram increase Levels of concentration increase, and users feel less distracted by external stimuli
Sunifiram also enhances long-term potentiation, which is the forming of new connections regarding memory storage.
Sunifiram has some anxiolytic benefits. Feeling more relaxed is beneficial when trying to focus.

 

Sunifiram DOSING
Like what was mentioned above, the typical dose for an adult human would be approximately 5mg of sunifiram. The strength of the effects are greater when it is taken sublingually (i.e. under the tongue) as opposed to just swallowing it. Don’t worry too much if you go over the standard dose, though! Sunifiram has extremely low toxicity and a huge range between therapeutic and dangerous amounts.

 

 

 

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