Tamoxifen Citrate (Nolvadex)

Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid.

General Details

Anti Estrogen Steroids USP Standard CAS 54965-24-1 Tamoxifen Citrate Nolvadex

 

Details:

 

Tamoxifen Citrate (Nolvadex)
Chemical Name: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxyl]-N,N-dimethyl-ethanamine-citrate;
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate
Molecular Formula: C26H29NO.C6H8O7
Molecular weight: 563.64
CAS NO.: 54965-24-1

Assay: 99.6%

 

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Appearance: white crystalline powder ; MP: 140-144 ºC
Standard: CP/2000; USP/26

 

Description:

Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: Rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.
The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex.
The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction  (individuals using anabolic steroids were not studied though) from use of Nolvadex.

 

Specification:

 

Product name Tamoxifen citrate (Nolvadex)
Appearance White crystalline powder
Identification IR , UV conform Conform
Loss on drying ≤0.5ml 0.21ml
Residue on ignition Not more than 0.2% 0.07ml
Iron Not more than 0.005% 0.0017%
Heavy metals Not more than 0.001% 0.0006%
Related substances Total: Not more than 1.0%
Individual: Not more than 0.5%
0.35%
0.13%
E-isomer Not more than 0.3% 0.18%
Organic volatile impurities Conforms Conforms
Assay 99.0~101.0% 99.6%

 

Applications:
For the treatment of advanced, recurrent breast cancer and ovarian cancer and other illnesses. Used as an antineoplastic raw materials.
Biological Activity: Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30.

 

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