Muscular Repair & Recovery
Between workouts, it is important for you to take the time to allow your muscles to recover. To optimise your training and achieve the muscle building goals you’ve been working so hard to accomplish you must enable your muscles to recover. Recovery is not falling into your nearest easy chair glued to your TV. Nor is it, allowing yourself the indulgences you’ve kept away from to achieve your goals. Serious planning for your off days is as important as the time you put in at the gym.
Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.
Myostatin (GDF-8) is a member of the transforming growth factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength.
Follistatin works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It’s also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.
Even though in bodybuilding circles we don’t hear much about Sermorelin, this doesn’t mean that this peptide does not have its uses. In fact, anti-aging and hormone replacement clinics have been prescribing it for years because it works as a clean GHRH. The problem for the bodybuilder or athlete is that it has a very short half-life of about ten (10) minutes.
HGH Frag 176-191 is a fragment of the HGH peptide. Scientists found that if they truncated the peptide at the C terminal region they could isolate the fat loss attributes associated with HGH. Taking this fragment from HGH, including the peptide bonds from 176-191, they found they had developed a peptide that regulated fat loss 12.5 times better than regular HGH.
BPC-157 is known for super quick and professional Joint/tendon/ligament healing in all phases of clinical trials. BPC-157 has been shown in studies to heal torn quadriceps muscles, detached achilles tendon, muscles that have been damaged/crushed. Demonstrating dramatic fast recovery from muscle tears. Tendon to bone healing – increased ligament healing, BPC-157 has a variety of protective effects in the organs.
Thymosin Beta-4 is a naturally occurring peptide present in almost all animal and human cells. TB500 is a synthetic peptide that has been directly linked to recovery as it is plays a vital role in building new blood vessels, new small muscle tissue fibers, cell migration and blood cell reproduction. If you are an injured athlete, all of these properties are something that becomes very desirable when looking to speed up the recovery process.
Even though in bodybuilding circles we don’t hear much about Sermorelin, this doesn’t mean that this peptide does not have its uses. In fact, anti-aging and hormone replacement clinics have been prescribing it for years because it works as a clean GHRH. The problem for the bodybuilder or athlete is that it has a very short half-life of about ten (10) minutes. This becomes an unattractive feature when compared to the half-life of MOD GRF (1-29) (CJC 1295 without DAC), which comes in around 30 minutes. Despite its short window, it does bind quite effectively to the pituitary receptors. The other main down side associated with its very short half life is that it is quickly broken down by blood enzymes within minutes. This is why a GHRH peptide with a half life of 30 minutes or longer is desirable, since it will survive the blood enzyme death and allow it to circulate the body looking for hormone receptors to bind to.
Hexarelin is another hexapeptide like GHRP-6. Unlink the other GHRP’s out there, Hexarelin is the dark horse, the black sheep, the underdog not usually mentioned and often over looked for certain qualities. This grossly underestimated peptide shouldn’t be pushed to the side, but rather examined to understand its benefits and usability for bodybuilders and athletes alike.