November 4, 2017

Difference Between Testosterone Cypionate and Testosterone Enanthate


What is testosterone cypionate ?What is testosterone enanthate ?

Enanthate is a European steroid while Cypionate is manufactured in the U.S. Testosterone Cypionate and Enanthate both steroids have the same effects and functions whilst there are studies claiming the longevity effect of Cypionate compared to Enanthate. However, the latter is known worldwide while Cypionate is only limited in the U.S. Testosterone Cypionate is one of the most effective hormones that can be used for various purposes while Enanthate is capable of staving off hormones that promote muscle loss and fat gain while increasing the person’s metabolic rate.


As people mature, they often realize that life is not about finding yourself (as they believed in their younger years), but about creating yourself. Some adults discover that Low T therapy helps them to do this; but which form of treatment do they choose, between testosterone enanthate vs. testosterone cypionate? And do they discuss their treatment options with their hormone replacement therapy medical providers before making their decision?

Whenever mature adults find themselves facing a medical issue, such as the development of a symptomatic hormone deficiency, they should always be able to discuss their medical treatment options with their healthcare providers. In today’s world, people no longer need to depend on their doctors to serve as their sole source for medical information on the health problems that occur to them; the Internet has changed all of that. But they should be able to rely on the doctors providing their medical care to advise them on their choices for treatment.

Adults who choose Nexel Medical for testosterone replacement therapy (TRT) will find that our doctors and clinical advisors can always be relied on to answer all of their questions about treating Low T, including the various forms of therapy that are available to them. They can easily obtain accurate and helpful information on all aspects of their treatment, including issues like using injectable testosterone enanthate vs. testosterone cypionate, or perhaps some other form of treatment altogether.

Unlike some medical practitioners, we always take the time to make sure that our patients, or patients-to-be, are comfortable and confident that they have received all of the information they need to make a knowledgeable decision about getting medical treatment for their problematic testosterone deficiency. We believe that they deserve to know what the pros and cons of their various options are, along with knowing what is likely to happen if they decide to let their hormone disorder go untreated – because we believe that mature and intelligent adults want and can handle the facts that are associated with any health problem that they are experiencing.


What is the difference between testosterone cypionate and testosterone enanthate ?

1. Enanthate is widely manufactured across the globe while cypionate is less popular outside the U.S.
2. Cypionate contains 8-carbon ester chains while Enanthate has 7. The greater the carbons present in the ester group, the less soluble it is in the water and the more it is oil-soluble. Cypionate then has longer active life.
3. Some body-builders claim that Cypionate gives more of a kick compared to Enanthate and is said to produce a higher level of water retention.
4. Most athletes opt to use Enanthate as this steroid is typically associated with anabolic steroids effects.
5. Cypionate is far more expensive than Enanthate.


Injectable testosterone cypionate vs testosterone enanthate:

In topically applied gel, skin patch and cream forms of TRT, the supplemental male hormone is absorbed through the layers of your skin to varying degrees of effectiveness. In the injectable forms of treatment for Low T, the testosterone in injected directly into your muscles, typically the glutes, thighs or deltoids. This is the original form of TRT and it is the one that is still the most widely prescribed by hormone replacement therapy doctors today, because they know how consistently effective it has proven to be.

But of the two most commonly prescribed injectable formulations, what are the pros and cons for patients regarding the use of testosterone enanthate vs. testosterone cypionate? Or are these pharmaceutically manufactured substances so similar that they are practically interchangeable? Let’s examine the individual characteristics of each so that you will be able to make an informed decision about which one you might prefer to use.

Testosterone Cypionate Injections:

  • Is a biochemically modified ester form of testosterone
  • Is widely available from licensed US pharmacies
  • Very affordable when self-administered
  • Longest-lasting, so requires the fewest number of injections
  • Is the most widely prescribed form by US doctors for their TRT patients
  • Provides flexibility in dosing, so that doctors can revised dosage as needed

Testosterone Enanthate Injections:

  • Is also a biochemically modified ester form of testosterone
  • Is the most widely prescribed form outside of the US
  • Very affordable when self-administered
  • Long-lasting; may require a slightly higher number of injections than cypionate
  • Also provides dosing flexibility
  • May not be as readily available from US pharmacies as the cypionate formulation

It is estimated that among all US men using treatment for Low T, approximately 65% are using a prescribed gel and approximately 30% use doctor prescribed testosterone injections. This is most likely due to the fact that general practitioners treating patients for testosterone deficiency tend to prescribe the topical forms far more often than the injectable forms. Among HRT specialists however, the use of testosterone enanthate vs. testosterone cypionate is an issue that is discussed with patients far more often, since this is the form of treatment that will typically be recommended to them. It is interesting to note that many men who become dissatisfied with the results of using a gel or cream, or find the daily application process and precautions intrusive to their lifestyles, often switch to the injectable form of treatment.

At Nexel Medical, our doctors primarily prescribe injectable testosterone cypionate; however, exceptions can be made to accommodate those patients who feel strongly about using the enanthate form or trying one of the topical forms.



All types of medications, non-hormones or hormones carry the possibility of negative side effects. When consumed in a large amount, testosterone can cause various side effects. As men age, the testosterone levels lessen that may lead to loss of muscle strength and mass, loss of sex drive, water retention, testicular shrinkage, and fat gain. Whichever you choose, Testosterone Cypionate or Enanthate, you should take it moderately. These steroids are ideal for middle to old-age individuals as it may delay or even prevent them from having Alzheimer’s disease as well as other cognitive disorders. It can also improve mood, appetite, sex drive and memory, protects the nerves, and aids in preventing osteoporosis. Furthermore, using steroids with the right dosage as testosterone replacement can boost one’s quality of life. Enjoy the benefits and avoid the possible health risks by using commercial steroids responsibly.


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