Dostinex (Cabergoline)

Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, Ndimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water. Cabergoline is a dopamine receptor agonist. It works by reducing the amount of prolactin (a hormone) that is released from the pituitary gland. Cabergoline is used to treat a hormone imbalance in which there is too much prolactin in the blood (also called hyperprolactinemia). Dostinex (Cabergoline) is a dopamine agonist. Dopamine is a chemical, found in the brain, which transmits nerve impulses and is involved in the formation of epinephrine. More likely than not, this is why the Life-Extentionistas are very big on this drug. Dopamine is also released by the hypothalamus, and hormone can inhibit the release of prolactin from the anterior lobe of the pituitary, so given all the bad things that we have already seen to be a result of excess

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General Details

Cutting Cycle Raw Cabergoline 81409-90-7 

 

Basic info:

 

Cabergoline
Alias:Cabaser,Dostinex;Dostine, 6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
CAS: 81409-90-7
Molecular Formula: C26H37N5O2
Molecular Weight: 451.6
Melting Point: 102-104° C
Purity:99.5%
Character:White Powder
Packing:Foil bag or as requirments
Manufacture:HKYCGC
Payment:T/T, Western Union and Money Gram
Delivery:Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door)

 

Description:
Cabergoline is a medicine used to treat hyperprolactinemia, a condition characterized by high levels of prolactin a natural substance in the body that helps breastfeeding women produce milk.Too much prolactin can cause health problems in men, and in women who aren’t breastfeeding.
Cabergoline is in a class of medicines knowns as dopamine receptor agonists.It works by stopping the brain from making and releasing the prolactin hormone from the pituitary gland. Cabergoline use is usually stopped when prolactin levels are normal for 6 months. It may be given again if symptoms of too much prolactin occur again.

 

Applications:

  • hyperprolactinemia
  • adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
  • monotherapy of Parkinson’s disease in the early phase;
  • combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson’s disease;
  • in some countries also: ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis andgalactorrhea);
  • treatment of uterine fibroids.
  • adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing growth hormone levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases; growth hormone and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when growth hormone secretion can not be sufficiently controlled by other methods;
  • Cushing’s disease – cabergoline may be used to lower ACTH levels and cause regression of ACTH producing pituitary adenomas;
  • other pituitary adenomas – cabergoline has demonstrated certain efficacy in controlling or reducing other kinds of pituitary adenomas, as well as silent or non-functional adenomas.

Dosage:
For disorders of high prolactin levels or pituitary tumors:
Adults—At first, 0.25 milligram two times a week. Your doctor may increase your dose every 4 weeks as needed, according to body prolactin levels, up to 1 mg two times a week.
Children—Use and dose must be determined by the doctor.
Storage:
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.

 

Dopamine Receptor Dostinex Caberlin CAS 81409-90-7 Cabergoline

 

 

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