Dyclonine Hydrochloride
Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt.
Dyclonine Local Anesthetic Agents 536-43-6 Dyclonine Hydrochloride Dyclonine HCL Powders For Topical Anesthesia
Basic View:
English name : dyclonine hydrochloride
English Name : Dyclonine, Hydrochloride; 4-butoxy-3-piperidinopropiophenone hydrochloride; Dyclonine HCL
CAS : 536-43-6
EINECS Number : 208-633-6
Formula : C18H28ClNO2
MW : 325.8734
Boiling point : 424.5 ° C at 760 mmHg
Flash Point : 210.5 ° C
Vapor Pressure: 2.06E-07mmHg at 25 ° C
Uses : For topical anesthesia
Assay : 99.72%
Appearance : White powder
COA:
| Items | Specifications | Results |
| Appearance | A white or almost white crystalline | A white powder |
| Identification | A,B,C in Pass | Complies |
| Melting Point | 173 – 178 ℃ | 174-177.5℃ |
| Acidity(PH) | 4.0 – 7.0 | 6.6 |
| Loss on drying | ≤ 1.0 % | 0.33 % |
| Residue on ignition | ≤ 0.2 % | 0.034% |
| Assay | 98 – 102 % | 99.72% |
| CONCLUSION | Pass USP 34 | |
Description:
Dyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungicidal activity. Self-sterilizing action manifested by preparations containing the drug was considerably enhanced upon the addition of chlorobutanol. Results of in vitro tests employing microorganisms commonly involved in local infections indicated that the two agents in combination act synergistically
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Applications:
Has been used as a local anesthetic agent prior to laryngoscopy, bronchoscopy, esophagoscopy, or endotracheal intubation.
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