Rimonabant

Rimonabant is a weight loss drug, Sanofi-Aventis by the French company successfully developed for the treatment of obesity is the first cannabinoid type 1 receptor (CB1) antagonist, by selectively blocking the EC system cannabis Su -1 (cannabinoid-1, CB1) receptors play a role, can significantly reduce weight, reduce waist circumference, reducing risk factors for cardiovascular disease, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for the existence of clinical obesity or heart disease risk for people.

General Details

Cas 168273-06-1 Powder Rimonabant Weight Loss Steroids For Body Shape

 

Quick details:

 

  1. Product name :Rimonaban
  2. Synonyms: ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716);5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide;A 281;Sr 141716
  3. CAS: 168273-06-1
  4. MF: C22H21Cl3N4O
  5. MW: 463.79
  6. Product Categories: Weight Loss;SR141716
  7. Mol File: 168273-06-1.mol
  8. Usage: Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane ;Mainly used for weight loss .
  9. Assay:99%
  10. Manufacturer:HKYCGC
  11. MOQ:10G
  12. Standard:USP

 

The certification of analysis for Rimonabant:

 

Test Items Specification Test Results
Description White or Almost White Crystalline Powder White crystalline powder
Identification IR , UV conform Conform
Loss on drying ≤0.5ml 0.21ml
Residue on ignition Not more than 0.2% 0.06ml
Iron Not more than 0.005% 0.0018%
Heavy metals Not more than 0.001% 0.0006%
Related substances Total: Not more than 1.0% 0.32%
Individual: Not more than 0.5% 0.14%
E-isomer Not more than 0.3% 0.19%
Organic volatile impurities Conforms Conforms
Assay 99.0~101.0% 99.51%
Conclusion Conform with USP30

 

Product description:

 

Rimonabant is a weight loss drug, Sanofi-Aventis by the French company successfully developed for the treatment of obesity is the first cannabinoid type 1 receptor (CB1) antagonist, by selectively blocking the EC system cannabis Su -1 (cannabinoid-1, CB1) receptors play a role, can significantly reduce weight, reduce waist circumference, reducing risk factors for cardiovascular disease, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for the existence of clinical obesity or heart disease risk for people.

 

Application :

 

Rimonabant for the new weight-loss drug, can be applied to smoking cessation. A new weight-loss drug rimonabant (Rimonabant), not only can lose weight, but also lower blood pressure, cholesterol and blood sugar, domestically year clinical study found that subjects taking one to two months later, weight Save an average of six to eight kilograms.

 

The other fuction of quit smoking :

 

Rimonabant may also be found to be effective in assisting some smokers to quit smoking. Sanofi is currently conducting studies to determine the possible value of rimonabant in smoking-cessation therapy. The Studies with Rimonabant and Tobacco Use (STRATUS) program involves more than 6,000 subjects. STRATUS is designed to explore two smoking-related therapies: first, to use rimonabant directly to aid in smoking cessation; second, to help prevent weight gain in former smokers. Initial results apparently suggest rimonabant is effective for both uses. However, the FDA has explicitly stated to Sanofi that, without additional studies, rimonabant cannot be approved in the United States for smoking cessation therapy.

 

Weight Loss Drug Rimonabant CAS: 168273-06-1

 

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Name Molecular Formula Formula Weight CAS
Rimonabant C22H21Cl3N4O 463.79 168273-06-1
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