SARMs
The term SARMS stands for “Selective Androgen Receptor Modulators.” Androgens are a class of hormones that serve as ligands that bind to cellular androgen receptors. The androgen receptor is involved in a complex signal transduction pathway that ultimately results in greater expression of specific genes.
AICAR
AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
GW-501516 (Cardarine)
GW stimulates glucose uptake and skeletal muscle tissue. It burns fat by stimulating fatty acid oxidation. It’s suggested as a potential treatment for obesity because of it’s ability to rapidly melt fat.
LGD-4033
LGD-4033 is a selective androgen receptor modulator (SARMS), and a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity.
MK-677 (Ibutamoren)
Ibutamoren (MK-677, L-163,191) is a drug which acts as a potent, orally active growth hormone secretagogue.
Andarine (S-4)
Andarine (GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy,[1] using the non-steroidal androgen antagonist bicalutamide as a lead compound.
Ostarine (MK-2866, Enobosarm)
Ostarine (MK-2866) is a SARM developed by GTx for the prevention and treatment of muscle wasting. It may eventually be a medical prescription for the prevention of cachexia, atrophy and sarcopenia as well as for Hormone or Testosterone Replacement Therapy.
- 1
- 2