Anastrozole (Arimidex)

Anastrozole is also called Arimidex. It is a type of hormone therapy called an aromatase inhibitor. Anastrozoles treats breast cancer in women who have had their menopause.

General Details

Bodybuilding Anabolic Steroids For Women Anastrozole / Arimidex Anti-Estrogen Powder 120511-73-1

 

Quick details:

 

Anastrozole

Alias: Arimidex

CAS No: 120511-73-1

MF: C17H19N5

MW: 293.37

Purity: 98%

Solubility: Insoluble

Appearance: white powder.

Grade Standard:Medicine Grade

Function:Hormones and Regulation of Endocrine Function of Drug.

STORAGE: Store anastrozoles tablets at room temperature, between 20 C – 25 C (68 F – 77 F).

 

Test Report:

 

COA:

 

Items Standard Results
Description White crystalline powder Complies
Identification IR
HPLC
Reactive
Conform with standard IR
Conform with standard HPLC
Conform
Solubility Freely soluble in methanol,acetone,
ethanol and tetrahydrofuran.
And very soluble in acetonitrile
Complies
Total Impurity max.0.5% 0.18%
Total Unspecified Impurity max. 0.2% 0.08%
Individual unspecified impurlty max. 0.1% 0.05%
Related compound B max. 0.2% 0.07%
Related compound C max. 0.2% 0.04%
Related compound D max. 0.1% 0.05%
Related compound E max. 0.1% 0.06%
Limit of cyclohexane max. 0.08% ND
Limit of ethylacetate max. 0.1% 0.07%
Melting point 81.0~84.0ºC 82.5~83.2ºC
Water max. 0.3% 0.21%
Residue on ignition max. 0.1% 0.07%
Heavy Metals max.0.001% Complies
Assay(HPLC) 98.0%~102.0% 99.8%
Storage Cool and dry
Conclusion It complies to USP32 .

 

Description:

 

Anastrozole is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer.

 

Anastrozole is also called Arimidex. It is a type of hormone therapy called an aromatase inhibitor. Anastrozoles treats breast cancer in women who have had their menopause.

Arimidex is the aromatase inhibitor of choice. Arimidex’s mechanism of action – blocking conversion of aromatizable steroids to estrogen – is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid)  (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others.

 

Anastrozole Application:

 

ARIMIDEX is approved for adjuvant treatment (treatment following surgery with or without radiation) of postmenopausal women with hormone receptor-positive early breast cancer.

ARIMIDEX is approved for the initial treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer and for the treatment of postmenopausal women with advanced breast cancer that has progressed following treatment with tamoxifen. Patients with hormone receptor-negative disease and patients who did not previously respond to tamoxifen therapy rarely responded to ARIMIDEX.

 

Anastrozoles can also Help Shrink Tumor and Slow Their Growth. Arimidex is a hormonal therapy used to treat breast cancer in women who have been through the menopause. Hormones are substances produced naturally in the body. They act as chemical messengers and help control the activity of cells and organs. Hormonal therapies work by interfering with the production or action of particular hormones in the body.

 

Anastrozoles has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism.
Some athletes and body builders use anastrozoles as part of their steroid cycle to reduce and prevent symptoms of excess estrogen–gynecomastia, emotional lability and water retention.
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