Flibanserin
Flibanserin, known as the "female Viagra", is a prescription medication used to enhance sexual desire and decrease emotional distress in premenopausal women with hypoactive sexual desire disorder (HSDD).
Flibanserin Treat Sex Steroid Hormones for Female Hypoactive Sexual Desire Disorder
Product Name Flibanserin
Chemical Name Centrophenoxine HCL
CAS Number 167933-07-5
EINECS Number 222-975-3
Molecular Formula C20H21F3N4O
Molecular Weight 294.17
Melting Point 139-143ºC
Assay 99.5%
Appearance White powder
What is Flibanserin?
Flibanserin, known as the “female Viagra”, is a prescription medication used to enhance sexual
desire and decrease emotional distress in premenopausal women with hypoactive sexual desire
disorder (HSDD). HSDD is the most commonly reported sexual dysfunction in women.
Although flibanserin has been called “the female Viagra”, the way in which it works is distinctly
different from Viagra. Viagra works by increasing blood flow to the genitals, whereas
flibanserin may work more like an antidepressant by correcting an imbalance of neurotransmitters in the
brain to help restore sexual desire. It has effects on dopamine, norepinephrine, and serotonin
levels in the brain.This medication may be prescribed for other uses. Ask your doctor or
pharmacist for more information.
Description
Flibanserin (INN, USAN), sold under the trade name Addyi, is a medication approved for the treatment of
pre-menopausal women with hypoactive sexual desire disorder (HSDD).The medication increases the
number of satisfying sexual events per month by about one half to one over placebo from a starting point
of about two to three.
Flibanserin ( Addyi ) is a new drug being investigated for the prevention of HSDD in woman. HSDD, is a
relatively new term developed to describe Hypoactive Sexual Desire Disorder which basically means a
woman whose is otherwise healthy has a lacking libido, or a lack of sexual desire. Studies show that
about 10-20% of women face this problem and some say HSDD outnumbers men with sexual problems.
Flibanserin is classified as a 5-HT serotonin receptor agonist and a dopamine D4 receptor partial
agonist. It is a Non-Hormonal agent that in essence increases dopamine and noradrenalin while
reducing Serotonin in the brain. This in return seemingly has a positive effect on a woman’s sexual
craving who was otherwise lacking in this area. The benefits of it being Non-Hormonal are that it will not
have the problems associated with other hormonal treatments such as a negative altered mood among
other issues.
Dosage
(1) Recommended dosage is 100 mg taken once daily at bedtime.
(2) Taking it at night reduces the risk of sleepiness, low blood pressure, and fainting during waking hours.
(3) If your symptoms do not improve after 8 weeks of treatment, stop treatment and call your doctor.
(4) If a dose is missed at bedtime, take the next dose at bedtime the following day. Do not take a double
dose to make up for a missed one.
Common side effects of flibanserin
(1) dizziness
(2) nausea
(3) Tiredness
(4) difficulty falling asleep or staying asleep
(5) dry mouth
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Flibanserin
Flibanserin, known as the "female Viagra", is a prescription medication used to enhance sexual desire and decrease emotional distress in premenopausal women with hypoactive sexual desire disorder (HSDD).